Literature about the Development of the CorTec Platform and Its Components

Kohler F, Gkogkidis A, Bentler C, Wang X, Gierthmuehlen M, Fischer J, Stolle C, Reindl L, Rickert J, Stieglitz T, Ball T & Martin Schuettler (2017): “Closed-loop interaction with the cerebral cortex: a review of wireless implant technology”, Brain-Computer Interfaces, 2017, 146-154

Boretius T, Schuettler M, Stieglitz T (2011): “On the Stability of Poly-Ethylenedioxythiopene as Coating Material for Active Neural Implants”. Artificial Organs 35(3), 2011, 245-248

Feili D, Schuettler M, Doerge T, Kammer S, Stieglitz T (2005): “Encapsulation of Organic Field Effect Transistors for Flexible Biomedical Microimplants”. Sensors and Actuators (A), No 120, pp. 101-109

Feili D, Schuettler M, Doerge T, Kammer S, Hoffmann K P, Stieglitz T (2006): “Flexible Organic Field Effect Transistors for Biomedical Microimplants Using Polyimide and Parylene C as Substrate and Insulator Layers”. Journal of Micromechanics and Microengineering, vol. 16, pp. 1555 – 1561

Feili D, Schuettler M, Stieglitz T (2008): “Matrix-addressable, active electrode arrays for neural stimulation using organic semiconductors – cyctotoxicity and pilot experiments in vivo”. Journal of Neural Engineering, vol. 5, pp. 68 – 74

Gkogkidis, Alexis C, et al. ”Closed-loop interaction with the cerebral cortex using a novel micro-ECoG-based implant: the impact of beta vs. gamma stimulation frequencies on cortico-cortical spectral responses.” Brain-Computer Interfaces (2017), 4:4, 214-224

Hassler C, von Metzen R P, Ruther P, Stieglitz T (2010): “Characterization of Parylene C as an Encapsulation Material for Neural Prostheses”. Journal of Biome-dical Materials Research B Appl Biomater., Epub ahead of print: Jan 29, 2010, DOI: 10.1002/jbm.b.31584, 93(1):266-274

Hassler C, Boretius T, Stieglitz T (2011): “Polymers for Neural Implants”. J Polymer Science Part B: Polymer Physics 49(1), 2011, 18-33

Henle C, Raab M, Doostkam S, Cordeiro J, Schulze-Bonhage A, Stieglitz T, Rickert J (2010), First long term in vivo study on subdurally implanted Micro-ECoG electrodes, manufactured with a novel laser technology. Biomedical Microdevices (in press) DOI: 10.1007/s10544-010-9471-9

Henle C, Madjarow A, Schuettler M, Stieglitz T (2010): “Cytotoxicity of  Laser-Fabricated Neural Electrode Arrays”. Proceedings of the Annual Conference of the German Society for Biomedical Engineering

Henle C, Hassler C, Kohler F, Schuettler M, Stieglitz T (2011): “Mechanical Characterization of Neural Electrodes based on PDMS – Parylene C – PDMS Sandwiched System”. Proc IEEE EMBS, 2011

Rubehn B, Bosmann C, Oostenfeld R, Fries P, Stieglitz T (2009): “A MEMS-based flexible multichannel ECoG-electrode array”. J Neural Engineering 6 (3), 036003

Rubehn B, Stieglitz T (2010): “In Vitro Evaluation of the Long-Term Stability of Polyimide as a Material for Neural Implants”. Biomaterials, Epub ahead of Print, 6. Feb 2010, doi:10.1016/j.biomaterials.2010.01.053, 31(13):3449-3458

Rylie A, Green R A, Ordonez J S, Schuettler M, Poole-Warren L A, Lovell N, Suaning G J (2009): “Cytotoxicity of Implantable Microelectrode Arrays Produced by Laser Micromachining”. DOI:10.1016/j.biomaterials.2009.09.099

Schuettler M, Stiess S, King B, Suaning GJ (2005): “Fabrication of Implantable Microelectrode Arrays by Laser-Cutting of Silicone Rubber and Platinum Foil”. Journal for Neural Engineering, pp. 121-128

Schuettler M, Franke M, Krueger T B, Stieglitz T (2008): “A Voltage-Controlled Current Source with Regulated Electrode Bias-Voltage for Safe Neural Stimulation (2008)”. Journal of Neuroscience Methods, vol. 171, pp. 248-252

Schuettler M, Ordonez J S, Silva Santisteban T, Schatz A, Wilde J, Stieglitz T (2010): “Fabrication and Test of a Hermetic Miniature Implant Package with 360 Feedthroughs”. Proceedings of the Annual International Conference of the IEEE EMBC, pp. 1586-1588

Schuettler, M, Schatz, A, Ordonez, J S, Stieglitz, T (2011): “Ensuring Minimal Humidity Levels in Hermetic Implant Housings”. Proceedings to the Annual Conference of IEEE EMBS, (2011). (in press)

Schuettler, M, Ordonez, J S, Schatz, A, Stieglitz, T (2011): “A Hermetic Implant Housing with Large Number of Electrical Feedthroughs, Transparent to Infrared Light and Magnetic Fields”. Proceedings of the Annual Conference of the German Society for Biomedical Engineering (2011). (in press)

Stieglitz T, Schuettler M, Koch K P (2004): “Neural Prostheses in Clinical Applications Trends from Precision Mechanics towards Biomedical Microsystems in Neurological Rehabilitation”. Biomedizinische Technik, vol 49 (4), pp 72-77

Stieglitz T, Schuettler M, Koch K P (2005): “Implantable Biomedical Microsystems for Neural Prostheses”. IEEE Engineering in Medicine and Biology, vol. 24, 5, pp. 58-65

Stieglitz T, Rubehn B, Henle C, Kisban S, Herwik S, Ruther P, Schuettler M (2009): “Brain–computer interfaces: an overview of the hardware to record neural signals from the cortex”. In: Progress in Brain Research – Chapter 20, Vol.175, pp. 297-315

Stieglitz T (2010): “Manufacturing, Assembling and Packaging of Miniaturized Neural Implants”. Microsystem Technologies, Epub ahead of Print, DOI 10.1007/s00542-009-0988-x, 16(5), 723-734

Literature by CorTec and Its Partners about the Neurobiological Basis of the Technology

Arieli A, Sterkin A, Grinvald A, Aertsen A (1996): “Dynamics of ongoing activity: explanation of the large variability in evoked cortical responses”. Science. 1996 Sep 27;273(5283):1868-71

Ball T, Demandt E, Mutschler I, Neitzel E, Mehring C, Vogt K, Ad Aertsen A, Schulze-Bonhage A (2008): “Movement Related Activity in the High Gamma Range of the Human EEG”. NeuroImage 2008 Jun;41(2):302-10

Ball T, Kern M, Mutschler I, Aertsen A, Schulze-Bonhage A (2009): “Signal Quality of Simultaneously Recorded Invasive and Non-Invasive EEG”. NeuroImage, 46(3):708-16

Ball T, Schulze-Bonhage A, Aertsen A, Mehring C (2009): “Differential representation of arm movement direction in relation to cortical anatomy and function”. Journal of Neural Engineering 6(1):016006

Ball T, Breckel T, Mutschler I,  Aertsen A, Schulze-Bonhage A, Hennig J, Speck O (2011): “Variability of fMRI-Response Patterns at Different Spatial Observation Scales”. Human Brain Mapping (in press)

Birbaumer N, Ghanayim N, Hinterberger T, Iversen I, Kotchoubey B, KĂŒbler A, Perelmouter J, Taub E, Flor H (1999): “A spelling device for the paralysed”. Nature. 1999 Mar 25;398(6725):297-8

Birbaumer N, Vaadia E (2009): “Brain-Computer-Interfaces and Neurofeedback”. Frontiers in Neuroscience, 3, 1, 94-95

Blumberg J, Rickert J, Waldert S, Schulze-Bonhage A, Aertsen A, Mehring C (2007): “Adaptive classification for brain computer interfaces”. Conf Proc IEEE Eng Med Biol Soc. 2007;2007:2536-9

Braun D, Aertsen A, Wolpert D M, Mehring C (2009): “Learning optimal adaptation strategies in unpredictable motor tasks”. Journal of Neuroscience 29(20):6472-8

Brötz D, Braun C, Weber C, Soekadar S, Caria A, Birbaumer N (2010): “Combination of Brain Computer-Interface Training and Goal Directed Physical Therapy in Chronic Stroke: A case report”. Neurorehabilitation and Neural Repair.

DĂŒmpelmann M, Ball T, Schulze-Bonhage A (2010): “sLORETA allows reliable distributed source reconstruction based on subdural strip and grid recordings”. Human Brain Mapping (accepted)

Gharabaghi A, Hellwig D, Rosahl S K, Shahidi R, Schrader C, Freund H J, Samii M (2005): “Volumetric image guidance for motor cortex stimulation: integration of three-dimensional cortical anatomy and functional imaging”. Neurosurgery. 2005 Jul;57(1 Suppl):114-20; discussion 114-20

Meier R, Dittrich H, Schulze-Bonhage A, Aertsen A (2008): Detecting epileptic seizures in long-term human EEG: a new approach to automatic online and real-time detection and classification of polymorphic seizure patterns”. J Clin Neurophysiol. 2008 Jun;25(3):119-31

Mehring C, Rickert J, Vaadia E, Cardoso de Oliveira S, Aertsen A, Rotter S (2003): “Inference of hand movements from local field potentials in monkey motor cortex”. Nature Neurosci 6(12): 1253-1254

Mehring C, Nawrot M P, Cardoso de Oliveira S, Vaadia E, Schulze-Bonhage A, Aertsen A, Ball T (2005): “Comparing information about arm movement direction in single channels of local and epicortical field potentials from monkey and human motor cortex”. J.Physiol. (Paris) 98:498-506

Pistohl T, Ball T, Schulze-Bonhage A, Aertsen A, Mehring C (2008): “Prediction of Arm Movement Trajectories from ECoG-Recordings in Humans”. J Neurosci Methods, 167/1 pp. 105-115

Pistohl T, Schulze-Bonhage A, Aertsen A, Mehring C, Ball T (2011): “Decoding natural grasp types from human EcoG”. (in press)

Rickert J, Cardoso de Oliveira S, Vaadia E, Aertsen A, Rotter S, Mehring C (2005): “Encoding of movement direction in different frequency ranges of motor cortical local field potentials”. Journal of Neuroscience Sep 28;25(39):8815-24

Rickert J, Riehle A, Aertsen A, Rotter S, Nawrot M (2009): “Dynamic Encoding of Movement Direction in Motor Cortical Neurons”. Journal of Neuroscience, 11/2009, 13870 – 13882

Stieglitz T (2006): “Neuro-technical Interfaces to the Central Nervous System”. Poiesis and Practice 4(2), pp. 95-109

Waldert S, Preissl H, Demandt E, Braun C, Birbaumer N, Aertsen A, Mehring C (2008): “Hand movement direction decoded from MEG and EEG”. Journal of Neuroscience 28(4):1000-1008

Literature about the Function of BMIs as a Control System

Brunner P, Ritaccio AL, Emrich JF, Bischof H, Schalk G (2011): “Rapid Communication with a ‘P300? Matrix Speller Using Electrocorticographic Signals (ECoG)”. Front Neurosci. 2011 Feb 7;5:5

Hochberg L R, Serruya M D, Friehs G M, Mukand J A, Saleh M, Caplan A H, Branner A, Chen D, Penn R D, Donoghue J P (2006): “Neuronal ensemble control of prosthetic devices by a human with tetraplegia”. Nature. 2006 Jul 13;442(7099):164-71

Leuthardt E C, Gaona C, Sharma M, Szrama N, Roland J, Freudenberg Z, Solis J, Breshears J, Schalk G (2011): “Using the electrocorticographic speech network to control a brain-computer interface in humans”. J Neural Eng. 2011 Jun;8(3):036004

Moritz C T, Perlmutter S I, Fetz E E (2008): “Direct control of paralysed muscles by cortical neurons”. Nature. 2008 Dec 4;456(7222):639-42

Velliste M, Perel S, Spalding M C, Whitford A S, Schwartz A B (2008): “Cortical control of a prosthetic arm for self-feeding”.  Nature. 2008 Jun 19;453(7198):1098-101

Literature about the Treatment of Chronic Pain with Motorcortex Stimulation

Bowsher D (1995): “The management of central post-stroke pain”. Postgrad MedJI; 71: 598-604

Brown J A (2001): “Motor cortex stimulation”. Neurosurg Focus 11 (3):Article 5

Drouot X, Nguyen JP, Peschanski M, Lefaucheur JP (2002): “The antalgic efficacy of chronic motor cortex stimulation is related to sensory changes in the painful zone”. Brain, 125, 1660-1664

Katayama Y, Fukaya C, Yamamoto T (1998): “Poststroke pain control by chronic motor cortex stimulation: neurological characteristics predicting a favorable response”. J Neurosurg 89:585–591

Kolodziej M, Hellwig D (2009): “Motorcortex-Stimulation in der Behandlung der neuropathischen Schmerzen: Grundlagen und Beispiele”. J Neurol Neurochir Psychiatr; 10 (1), 74-80

Kumar B, Kalita J, Kumar G, Misra U K (2009): “Central Poststroke Pain: A Review of Pathophysiology and Treatment”. Pain Medicine Vol. 108, No. 5, May 2009, 1645-1657

Literature about Post-Stroke Rehabilitation Using Brain Stimulation

Caria A, Weber C, Brötz D, Ramos A, Ticini L F, Gharabaghi A, Braun C, Birbaumer N (2011): “Chronic stroke recovery after combined BCI training and physiotherapy: a case report”. Psychophysiology. 2011 Apr;48(4):578-82. doi: 10.1111/j.1469-8986.2010.01117.x

Harvey R L, Winstein C J; Everest Trial Group (2009): “Design for the everest randomized trial of cortical stimulation and rehabilitation for arm function following stroke”. Neurorehabil Neural Repair. 2009 Jan;23(1):32-44

Huang M, Harvey R L, Stoykov M E, Ruland S, Weinand M, Lowry D, Levy R (2008): “Cortical stimulation for upper limb recovery following ischemic stroke: a small phase II pilot study of a fully implanted stimulator”. Top Stroke Rehabil. 2008 Mar-Apr;15(2):160-72.

Jackson A, Mavoori J, Fetz E E (2006): “Long-term motor cortex plasticity induced by an electronic neural implant”. Nature. 2006 Nov 2;444(7115):56-60

Plow E B, Carey J R, Nudo R J, Pascual-Leone A (2009): “Invasive cortical stimulation to promote recovery of function after stroke: a critical appraisal”. Stroke. 2009 May;40(5):1926-31