Cytokine storm is a situation in which the response of the immune system gets out of hand, such that it actually causes more harm than good. The condition has received increased attention in the SARS-CoV2 pandemic, as it’s a serious complication of COVID-19. Cytokine storm means that there is an excessive release of cytokines flooding […]
Against the Storm with the Vagus Nerve Read More »
CorTec is part of an international clinical study that will enable severely paralyzed people to communicate again – with the help of an implantable brain-computer interface. It is a vision that has been at the core of CorTec’s DNA since its inception more than 10 years ago by now: Brain-Computer Interfaces (BCI) that enable severely
Speak your mind! – Pilot clinical study with severely paralyzed patients Read More »
For a project recently accepted for funding by the NIH, CorTec will supply novel electrodes to help people regain sensation from missing limbs. Losing a limb not only severely impairs our motor abilities, but also significantly impairs our level of independence. While prostheses can help to regain mobility, one of their biggest shortcomings is
Getting back that feeling. Read More »
The proprietary CorTec neuromodulation system “Brain Interchange” was developed for the discovery of novel neurotherapies. With funding by the US-American National Institutes of Health (NIH), and in collaboration with one of the world leaders in the field, Professor Dr. Jeff Ojemann and his team from the University of Washington School of Medicine in Seattle,
With the support of the Netherlands Organisation for Scientific Research, a new research network was established in 2021 that aims to develop new neurotechnological therapies for blindness, deafness, paralysis, and epilepsy. By combining recent knowledge about the brain with new possibilities within neurotechnology, the network’s approach is to establish high-bandwidth, wireless interfaces to the human
INTENSE: Dutch neurotechnology network on brain-machine interfaces Read More »
When electrically stimulating a nerve to modulate a specific body function for treating a disease, it is essential to know exactly what you are doing. Peripheral nerves typically are heterogeneous bundles of fiber groups (fascicles) that can carry a variety of functionally different signals from or to different body parts. To evoke a specific response,
Looking Inside of Nerves – a New Tool for Bioelectronic Medicine Read More »
Electrically stimulating the spinal cord can be an effective therapy for different kinds of treatment-resistant chronic pain. The exact mechanisms through which the stimulation suppresses pain are still not fully understood. In most systems currently used in patients, the electrodes are placed epidurally into the spinal cord canal. There is evidence that the stimulation effects
A novel wireless research device for chronic pain relief Read More »
Inflammatory reactions are supposed to eliminate pathogens in our bodies. Unfortunately, they sometimes get out of control, eventually causing more serious damage than the pathogens themselves. Such overshooting inflammatory responses are, for example, one of the causes for severe cases of the Covid-19 disease, but also frequently occur in other inflammatory diseases that often become
Specifically calming down the inflammatory system by nerve stimulation near the spleen Read More »
To make your research easier, we are constantly working on our products and our technology. But how to implant a Spiral Cuff in particular? Here we provide the ultimate How-To-Guide for your next application. Learn more about the various °AirRay Cuff Electrode Designs. Download the Guide “How to Handle a Spiral Cuff” here
How to Handle a Spiral Cuff Electrode Read More »
Delivering electrical currents to nerves can not only serve to stimulate them, by inducing action potentials that are carried along the nerve and finally activate the end organ (e.g., a muscle). Certain stimulation patterns can also suppress nerve activity, leading to an inhibitory effect on the respective end organs. This is of specific interest for
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FEATURE
Recording channels
Sampling rate
Sampling dynamic range
High pass filter cut-off
Low pass filter cut-off
Amplifier band pass gain
Band pass roll-off
Reference
Stimulation
Stimulation channels
Current
Current source
Pulse width
Power supply
Wireless data transmission
Closed Loop latency
VALUE
32
1 kHz
16 bit (74 nV smallest increment)
ca. 2 Hz
325 Hz
Adjustable: 100-750
20 dB/dec
Any (subset) of the recording channels selectable by software or one dedicated hard-wired additional contact
Current-controlled, biphasic, rectangular, asymmetric stimulus pulses (cathodic amplitude with pulse width followed by an anodic counter pulse of 1/4x amplitude and 4x pulse width)
32
Max. -6 mA / +1.5 mA (24 µA increments) within
compliance voltage range of -11 V to +5 V
Can be directed to any of the 32 electrode contacts
Negative phase: 10 µs – 2,500 µs
Wireless inductive, 120-140 kHz
Bi-directional, radio frequency in 2400-2483.5 MHz band ≤ 40 ms
