User Stories

Precision in the Peripheral Nervous System

How imec is advancing bioelectronic medicine   The medicine of the future will increasingly rely not just on chemistry, but on precision electronics. Our partner imec is advancing a new, minimally invasive technique for selective stimulation of the peripheral nervous system (PNS). While peripheral nerve stimulation is already an established treatment modality, current methods often […]

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A Software Interface for Developing Next Generation Neurotherapies

Closed-Loop Platform for Neurotherapy – NIH-funded Project for Stroke Rehabilitation   The first “brain pacemakers”, developed several decades ago, stimulated a specific area of the brain constantly, regardless of the patient’s condition. The stimulation parameters could only be changed by the attending physician. Because this approach cannot respond quickly to changes in the patient’s condition

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AirRay Sling Cuff electrode wrapped around fingers - CorTec GmbH

Relax and learn! The vagus nerve also supports motor learning.

The vagus nerve is the major constituent of the parasympathetic nervous system. Together with the antagonistic sympathetic system, it forms the autonomic nervous system, which regulates lots of reflexes and organ functions. The vagus is usually associated with “rest and digest” or “feed and breed” type of behaviors, as opposed to the ”fight or flight”

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Going through the pain to heal

It has been known for a long time that the vagus nerve can mediate anti-inflammatory responses. These reactions help lower body temperature and keep cytokine production at bay. This is why the vagus nerve is the target of many bioelectronic approaches for treating inflammatory diseases. Interestingly, however, the anti-inflammatory vagus response can also be induced

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The long and winding road towards specific vagus nerve modulation

The vagus nerve is one of the biggest cranial nerves. It interconnects the brain with almost all internal organs, including the heart, the respiratory tract, the kidney, and the digestive tract. It mediates important reflexes for autonomic functions and modulates a wide range of body functions, making it an attractive target for bioelectronic interventions. On

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